Which finding would indicate heparin-induced thrombocytopenia (HIT) during heparin therapy?

Which finding would indicate heparin-induced thrombocytopenia (HIT) during heparin therapy?

• A. Platelets rise above baseline after starting heparin.
• B. Platelet count remains normal with no new symptoms.
• C. A significant drop in platelets from baseline within days of starting heparin.
• D. Development of rash at injection site.

Answer: (C)